• Semax 0.1% 3 ml №1

Semax 0.1% 3 ml №1

Description for Semax 0.1% 3 ml №1

Trade name: Semax
Chemical name: methionyl-glutamyl-histidyl-phenylalanyl-prolyl-glycyl-proline
INN: methionyl-glutamyl-histidyl-phenylalanyl-prolyl-glycyl-proline

Pharmaceutical form: Nasal drops 0.1%
Ingredients: Semax in 100% stuff - 1 g, metilparagidroksibenzoata (Nipagin) - 1 g, purified water to 1 liter.

Description: Colorless transparent liquid.
Pharmacotherapeutic group. Nootropic drugs.
ATC code - [N06BX]

Pharmacological properties. Semax nasal drops 0.1% - The original synthetic peptide preparation, which is the analogue of a fragment of adrenocorticotropic hormone (AKTG4-10) (methionyl-glutamyl-histidyl-phenylalanyl-prolyl-glycyl-proline) is completely devoid of hormonal activity. All the amino acid L-shape.

Pharmacodynamics. Semax nasal drops 0.1% has an original mechanism neurospecific action on the central nervous system (CNS). Semax nasal drops 0.1% synthetic analogue of corticotrophin possessing nootropic properties, and completely devoid of hormonal activity. The drug affects the processes associated with memory formation and learning. Semax nasal drops 0.1% enhances attention in training and analysis of information, improves the consolidation of the memory trace, improves adaptation to hypoxia, cerebral ischemia, anesthesia and other damaging influences. The drug is practically non-toxic in single and prolonged administration. Shows no allergic, embryotoxic, teratogenic and mutagenic properties. Has no local irritating action.

Pharmacokinetics. Absorbed from the mucosa of the nasal cavity, while digested to 60-70% in terms of active substance. Semax nasal drops 0.1% rapidly distributed to all organs and tissues, crosses the blood-brain barrier. When injected into the blood Semax nasal drops 0.1% are fairly rapid degradation and removal from the body with urine.

Indications for use.

Intellectual and mental disorders in vascular lesions of the brain, post-traumatic brain injury, neurosurgery, and anesthesia, distsirkulyarnaya encephalopathy, transient ischemic attacks (TIAs), and neurotic disorders of various origins, including after ionizing radiation, the recovery period after stroke. To increase the adaptive capacities of the human body in extreme situations, prevention of mental fatigue in a monotone operator activity in the most intense periods of work in stressful conditions.

In ophthalmology Semax is used in optic atrophy, neuritis inflammatory, toxic-allergic etiology.

In pediatrics: as nootropic drugs in children aged 5 years in the treatment of minimal brain dysfunction (including ADHD - attention deficit disorder with hyperactivity).

Contraindications. Hypersensitivity to the drug. Children under 5 years old. Pregnancy, lactation, acute psychosis, a disorder accompanied by anxiety, convulsions in history.

Side effects. With prolonged use may mild irritation of the nasal mucosa.

Dosage and administration.
Semax applied intranasally, using a bottle sealed with a plastic cap-dropper.



Carefully cut off the tip of the pipette at the location specified in



The cap should be tightly closed dropper



Turn the bottle and it is easy to tapped his finger on the bottom, wait for the liquid filled the entire space pipettes



Remove the cap and a light pressure on the wide part of the pipette, squeeze the required number of drops of the drug in the nasal passage (the mucosa)

Drug store in tightly closed cap, as shown in

In one drop of standard solution containing 50 mg of active ingredient. Pipette solution of the drug in an amount not more than 2-3 drops put into each nostril. If necessary, increase the dosage of the introduction is carried out in stages at intervals of 10 - 15 minutes.

Single dose of 200 - 2000 mcg (based on 3 - 30 mg / kg).
Daily dose of 500-5000 mg (estimated 7-70 mg / kg).

Drug is prescribed daily for 3 - 5 days, if necessary, treatment extend to 14 days.

In diseases of the optic nerve agent instill 2-3 drops in each nostril 2-3 times a day. Daily dose of 600-900 mg / day. The treatment course of 7-10 days. In addition, the drug can be administered by endonasal electrophoresis. The drug is introduced to the anode. The current strength of 1 mA, duration of exposure 8 -12-15 minutes.
Daily dose of 400-600 mg / day. The treatment course of 7-10 days.

In Pediatrics:
With minimal brain dysfunction drug instill 1-2 drops in each nostril 2 times a day (morning and afternoon). Daily dose of 200-400 mg / day. The treatment course of 30 days.

Overdose (intoxication) drug.
Manifestations of overdose so far failed to identify even with a significant increase in single dose.

Interaction with other drugs.
Pharmaceuticals. Based on the chemical structure of drug availability chemically incompatible combinations are not supposed to: the drug is rapidly destroyed in the gastrointestinal tract is not entered.
Pharmacokinetic. Given the chemical structure of the drug (heptapeptide - a synthetic analogue of adrenocorticotropic hormone, completely devoid of hormonal activity), the speed of suction and speed of receipt of the blood, as well as the intranasal route of administration, the influence of other drugs on the pharmacokinetic parameters Semax nasal drops 0.1% is not assumed. Given the method of introducing Semax nasal drops 0.1% (intranasal) is undesirable introduction of having local vasoconstrictor effect in their intranasal administration.

Release form.
3 ml vial, sealed with a plastic cap-dropper. Each vial with instructions for use are packaged in a stack of cardboard.

Storage conditions.
List B. In sheltered from the light, at a temperature not exceeding +10 ° C, avoid freezing. Keep out of reach of children.

Shelf life: 2 years.
Do not use after the expiration date printed on the packaging.

Semax 0.1% 3 ml №1

  • Product Code: 29
  • Availability: In Stock
  • $55.00

  • Ex Tax: $55.00

Tags: Semax 0.1% 3 ml №1