Phosphatidylcholine - Essentiale N ampoules for liver health and more

About Essentiale N ampoules

Impaired liver function negatively affects the overall quality of life and affects appearance. The problem can be identified by the following symptoms: swelling, frequent bouts of nausea, possible vomiting, bitterness in the mouth, yellow coating on the tongue, insomnia, a constant feeling of fatigue and drowsiness, as well as regular pain in the right hypochondrium. As a rule, this is the result of frequent intake of fatty and unhealthy foods, alcohol, medications, infectious and viral diseases.

The use of Essentiale N ampoules, which contain 250 mg of essential phospholipids (EPL), will help stabilize digestive organ function. The active substance is phosphatidylcholine replaces and regenerates phospholipids at the cellular level, restoring and renewing them.

The Science Behind Phosphatidylcholine

As a result of research conducted by a large number of scientists, it can be confidently stated that phosphatidylcholine has the ability to protect liver cells from the effects of toxic substances such as ethanol, carbon tetrachloride, trichlorethylene (part of dry cleaning products), and fungal toxins. Phosphatidylcholine is present in the structure of lipids that circulate in the blood, and is also the main component of bile, which must be present for normal absorption of fats. It also reduces the body's ability to absorb cholesterol from foods.

For normal digestive organ function, constant renewal of cell membranes is necessary. And phosphatidylcholine in the liver is a building material for hepatocytes (liver cells) and their constant protection.

Key advantages of Essentiale N ampoules

Essentiale N ampoules have a number of distinctive advantages:

  • have membranotropic properties;
  • improve metabolism;
  • have a hepatoprotective effect;
  • stabilize carbohydrate and lipid metabolism;
  • effectively improve the functional state.

Unique composition of phospholipids Essentiale

The active ingredient of the drug containsEPL substance (diglyceride esters of choline phosphoric acid - phosphatidylcholine). In percentage terms: linoleic acid is approximately 70%, and the remaining 30% is linolenic and oleic acids.

During intravenous therapy, essential phospholipids rapidly interfere with the process of liver metabolic disorders. Penetrating easily into the cell membrane, they connect with endogenous phospholipids. This leads to an improvement in the patient’s clinical condition and has a positive effect on laboratory tests.

Understanding Phospholipids

Phospholipids are essential substances in the human body that perform a number of important tasks:

  • are the building material of cell membranes;
  • take part in the movement of fats, cholesterol, fatty acids;
  • help restore damaged tissue;
  • control the processes of cell growth and “death”;
  • influence the activity of certain enzymes.

Phospholipids in the required quantities are not produced by the body, but are taken in with food. They are embedded in the cell membrane and affect its restoration. They are excreted through the biliary tract and due to this, the lithogenic index of bile and its regulation are reduced.

The role of phosphatidylcholine in the body

Due to the fact that the liver is the main filter of the body and it is where the first blow of toxins, such as alcohol, medicines, poor-quality food and drinks, etc., is directed, it requires restoration much more often than other organs. In order for the liver to work like a high-quality clockwork mechanism, it must be “fed” with such an essential component as phosphatidylcholine.

More phosphatidyl-choline has a positive effect on cognitive functions such as memory and concentration. With its help, cholesterol in the blood is diluted, which minimizes the risk of cardiovascular diseases. Promotes the emulsification of fats in food, making them better absorbed by the body.

Soybean and Soybean Phospholipids: A Closer Look

Legume plants and soy known to mankind for more than one millennium. A very long time ago, the importance of beans was mentioned in books during the time of Emperor Sheng Nung, who lived and reigned in 2838 BC. Even then, legumes were one of the “five holy grains,” without which it was impossible to live a full life.

Where is phosphatidylcholine found?

The largest amount of it is found in soybeans, legumes, eggs, cod, beef liver, milk and broccoli.

In total, there are approximately 800 different types of soybean crops today. They consist of 35-40% proteins, 20-30% carbohydrates and 5-10% additional substances. During processing of legume oil, 30-45% soy lecithin orPhosphatidylcholine. It is this component that is used in pharmaceuticals for the production of hepatoprotective drugs.

Product Details

The Essentiale N is produced in the form of a solution that is administered intravenously. Prescribed to protect and restore organ function . The package contains 5 ampoules of 5 ml.

Essentiale N ampoules: Ingredients and composition

Contents of 1 ampoule of Essentiale N (5 ml):

  • Active ingredient: "essential phospholipids", which corresponds to EFL-Essence (diglyceride esters of choline phosphoric acid of natural origin with a high content of unsaturated fatty acids, the main part is linoleic (70%), the rest is linolenic and oleic acids) - 250 mg.;
  • Excipients: benzyl alcohol, deoxycholic acid, sodium chloride, sodium hydroxide, dye - riboflavin, water for injection.

Sourcing and quality of ingredients

All ingredients used for essential preparations are certified and meet the required quality level.

Phosphatidylcholine IV Therapy: Review and Benefits

Therapy with phosphatidyl choline IV has a beneficial effect on liver function and on the condition of the body as a whole, as evidenced by the following facts:

  • restoration of damaged cell membranes;
  • protection of cells and tissues from destruction due to the influence of external factors;
  • is a component of bile;
  • accelerates fat metabolism;
  • controls the metabolism of cholesterol in the blood at the required level;
  • has a beneficial effect on the transmission of nerve impulses from the brain to the muscles;
  • has a positive effect on brain performance;
  • promotes weight loss;
  • reduces the risk of malignant tumors, the appearance of dementia, Alzheimer's disease and other problems;
  • delivers and distributes lipids and fat-soluble vitamins in the body;
  • improves quality of life, sleep, cognitive health, memory, concentration.

How to use Essentiale N ampoules

The remedy is administered intravenously. The contents of preparation

 ampoules are diluted with the patient’s blood in a 1:1 ratio. If it is not possible to use your own blood, you can replace it with solutions that do not contain electrolytes. For example, it could be a 5% or 10% glucose solution (1:1) or a 5% xylitol solution.

Recommended dosage and use phosphatidyl choline

For adults and children, the medicine is administered slowly intravenously. Usually prescribed 5-10 ml per day. In more severe cases, the dose can be increased and range from 10 to 20 ml per day. When diluting the drug, it is recommended to use the patient’s own blood in a 1:1 ratio. Intravenous injections are usually given over 10 days.

Phosphatidyl choline IV: instructions for use

The ampules are prescribed intravenously when a faster and more powerful effect is required compared to capsule drugs. Sometimes during intravenous therapy with IV phosphatidylcholine, the doctor prescribes the drug in capsules at the same time to enhance the effect.

Best practices for storage and handling of the preparation

The shelf life of the phospholipids is 3 years. Ampoules should be stored in a dry place, inaccessible to children and pets, at a temperature between +2°С to 8°С.The ideal place is a refrigerator for medications.

Opened and incompletely used ampoules with the drug must be disposed of and cannot be reused.

Clinical studies and effectiveness

Conducted studies have proven the effectiveness of the phospholipids. After a course of taking Essentiale N, patients felt much better, symptoms of liver disease disappeared, general health became better, etc.

It has been clinically proven that ampules of preparation interact well with other drugs to enhance and expand therapy.

Review of studies on phosphatidyl choline function

In 2016, scientist K.J. Gundermann presented the results of 20 independent studies that were aimed at finding out how phosphatidyl choline affects the digestive organ. Phospholipids had a beneficial effect on people with the following pathologies: nausea, general weakness, bloating. After taking the drug, the problems disappeared. An improvement in the quality of blood plasma was noticed. The efficiency of using a PC was approximately 81%, which indicates an excellent result.

After the studies, the positive effect of phosphatidylcholine on liver restoration at the cellular level was proven. Using intravenous phosphatidyl choline, human organism resistance to the action of pathogenic factors is observed, functional activity is regulated, and reparative and regenerative processes in the organ are enhanced.

Essential phospholipids: Clinical data

By interfering with liver metabolic disorders, essential phospholipids penetrate the cell membrane and combine with endogenous phospholipids. Essential phosphatidylcholine improves the clinical status of the patient and laboratory parameter.

EPL substance (essential phospholipids): Research results

Studies have shown that essential lipids ideally replace endogenous ones, that is, native lipids synthesized by the body. They “calculate” the damaged ones and force them out of the cell, integrating and taking their place.

Safety and legal information

The phosphatidylcholine is safe for use in doses prescribed by a doctor. Sold in pharmacies with a prescription. Essentiale N has been certified in the USA.

Indications and contraindications

Like any drug, phosphatidylcholine has its own indications and contraindications.


  • fatty liver;
  • cirrhosis;
  • any form of hepatitis (acute or chronic);
  • liver cell necrosis;
  • hepatic coma and precoma;
  • toxic liver damage;
  • toxicosis during pregnancy;
  • treatment before and after surgery hepatobiliary zone areas;
  • psoriasis;
  • neurodermatitis;
  • radiation syndrome.


  • individual sensitivity or allergic reaction to at least one component;
  • children under 12 years old.

MPrecautions when using phosphatidylcholine

During pregnancy and lactation, use phosphatidylcholine only as prescribed by a doctor. Overdose may cause gastrointestinal upset.

Electrolyte solutions should not be used to dilute the drug.

Compliance with legal and regulatory requirements

The medical drug has passed the necessary clinical trials and is certified according to all established requirements.

Phosphatidylcholine (Essentiale N ampoules 250 mg / 5 ml №5)

  • Product Code: 52
  • Availability: In Stock
  • $29.30

  • Ex Tax: $29.30

Tags: Essentiale N ampoules 250 mg / 5 ml №5